FOA issued by the NCI, encourages research grant applications on the discovery and characterization of non-coding (nc) RNAs in preneoplasias and early stage cancers to: 1) improve early cancer detection, intervention, and prevention; 2) predict risk of progression from preneoplasia to cancer, and 3) distinguish benign lesions from precancerous lesions.  http://grants.nih.gov/grants/guide/pa-files/PA-09-199.html  FOA for R21 also issued.